Whatwedo

From idea to impact

We transform Oxford’s world-leading science into world-changing, billion-pound companies, solving global challenges and delivering strong returns for investors.

OXFORD’S SPINOUT REVOLUTION

Oxford University is the UK’s, and one of the world’s, leading engines for science-led company creation.

2000-2004
34
2005-2014
52

OSE established 2015

Click to see OSE's spinouts

2015-2019
82
2020-2024
100+
Companies

OSE IN NUMBERS

The world’s largest venture builder dedicated to a single university

+

flagship portfolio
companies

+

global co-investors

£

bn+

invested by OSE
and co-investors

 exits

of significance,
plus 2 NASDAQ IPOs

£

m+

realised to date
(9x headline multiple)

£

bn

Net Asset Value (NAV)

THE OSE ADVANTAGE

Unique
partnership

Strategic relationship with the University of Oxford.

 

60+ team embedded in Oxford’s innovation ecosystem.

World-leading science

Unrivalled access to
Oxford’s scientific IP.

 

Breakthroughs across quantum, AI, healthtech, climate, and life sciences.

Proven
model

A venture building engine, translating science into high-value companies.

 

Systematically creating 8–10 new ventures a year, set to double by 2030.

World-class portfolio

50+ breakout companies now scaling, with a strong pipeline of spinouts emerging.

 

Track record of success: Oxford Ionics, the UK’s first $1bn+ deep science spinout.

As our first generation of companies matures, OSE is entering a new phase – building the next wave of companies while our portfolio is forecast to deliver realisations, returns, and NAV growth.

OUR EXITS

Acquired by IonQ for $1.075bn

Validating the OSE model, this acquisition will accelerate scalable, energy-efficient quantum computing, with Oxford set to become the R&D centre for a global quantum superpower.
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Acquired by AbbVie for $255m

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Acquired by Gilead for $405m

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Acquired by Mercedes-Benz

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Acquired by Exact Sciences for $410m

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OUR SECTORS

Deep Tech

Quantum computing, AI, fusion energy, robotics – reshaping how the world is powered, built, and connected.

Discover Deep Tech

Life Sciences

Drug discovery, novel therapeutics, new approaches – advancing medicine to prevent, treat and cure disease.

Discover Life Sciences

HealthTech

Diagnostics, devices, digital tools – reimagining care, accelerating research, and advancing global health.

Discover HealthTech

STORIES

Oxford Ionics: Reimagining quantum computing

When two Oxford scientists found a way to build scalable quantum computers, and honed their approach over a decade, the potential was huge. Their breakthrough laid the foundation for world-record beating startup Oxford Ionics.

Founded by Dr Chris Ballance (CEO) and Dr Tom Harty (CTO), Oxford Ionics is delivering some of the most powerful quantum systems the world has ever seen – and it’s now a $1bn business.

It’s a story of cutting-edge science, bold ambition, and patient capital turning breakthrough research into world-changing potential.

Backed early by OSE, Chris and Tom have broken new ground in the use of ‘trapped-ion qubits’ – atoms suspended a hair’s width above a microchip. Their work enables quantum states with unprecedented stability, scalability, and precision.

Building a $1bn business doesn’t happen alone. OSE’s early belief in our vision and hands-on support gave us the confidence and resources to scale faster than we ever could have imagined.
Dr. Chris Ballance
Founder & CEO, Oxford Ionics
Oxford researchers & innovators
Working on cutting-edge research? Let’s explore its potential together.
Start the conversation
Shareholders
Interested in owning shares in OSE?
Contact our team
Co-investors
Ready to back Oxford’s most exciting spinouts?
Explore opportunities

WORK WITH US

Oxford researchers & innovators

Want your research to have real-world impact?

We partner with researchers and innovators across Oxford, Harwell and Culham to explore commercial potential, co-create ventures and build companies.

Start the conversation

Investors

Interested in becoming an OSE shareholder?

We’ve raised over £850m from global investors keen to access Oxford’s diverse, world-leading science. Our shareholders don’t just back OSE – many also co-invest alongside us.

Contact our team

Co-investors

Looking to invest in Oxford’s most exciting companies?

We partner with specialist global investors to fund and scale our companies – from pre-seed to growth. Together, OSE and our co-investors have invested more than £3bn.

Explore opportunities
OSE Manager Limited, a wholly owned subsidiary of Oxford Science Enterprises plc, is authorised and regulated by the Financial Conduct Authority.